mRNA-seq of retinoblastoma samples

NIAID Data Ecosystem2026-05-01 收录

视网膜母细胞瘤分子表达谱

类器官疾病模型

数据链接：

https://www.ncbi.nlm.nih.gov/sra/ERP128205 数据链接链接失效反馈

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RNA-seq analysis of five retinoblastoma tumor samples to compare expression signature with retinal organoids generated from hESCs in vitro and modelling retinoblastoma

创建时间：

2023-10-13

Patient-Derived Nasopharyngeal Cancer Organoids for Disease Modelling and Radiation Dose Optimization

鼻咽癌放射治疗优化

类器官疾病模型

Background: Effective radiation treatment (RT) for recurrent nasopharyngeal cancers (NPC), featuring an intrinsic hypoxic sub-volume, remains a clinical challenge. Lack of disease‐specific in-vitro m

NIAID Data Ecosystem70

TGFβ signaling directs serrated adenomas to the mesenchymal colorectal cancer subtype [organoids]

结直肠癌亚型转化机制

类器官疾病模型

The aim of this study was to determine the effects of TGFβ at the premalignant stage of CRC development. Organoid cultures were isolated from normal colon and from tubular adenomas. One normal colon c

NIAID Data Ecosystem40

Patient-derived brain organoids uncover reversible cellular abnormalities in Pitt-Hopkins Syndrome II

Pitt-Hopkins综合征

类器官疾病模型

We evaluate cellular phenotypic abnormalities and alterations in molecular pathways due to mutations in the gene TCF4 in cells derived from Pitt-Hopkins patients, in comparison with respective control

NIAID Data Ecosystem20

Transcriptional profiling of organoid glomeruli isolated from human kidney organoids modelling congenital nephrotic syndrome

类器官疾病模型

细胞转录组学

To investigate the impact of various NPHS2 homozygous point mutations on podocyte biology in induced pluripotent stem cell (iPSC)-derived human kidney organoids, an iPSC allelic series was generated f

NIAID Data Ecosystem40

Conserved proteomic programs between human cerebral tissue and organoids implicate RUVBL2 in neurodevelopment and disease

发育蛋白质组学

类器官疾病模型

Cerebral organoids have emerged as faithful humanoid avatars for modeling numerous advanced neurodevelopmental and pathological processes and additionally serve as a powerful discovery platform for le

NIAID Data Ecosystem30

mRNA-seq of retinoblastoma samples

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