Crystal structure of the catalytic domain of MMP-13 complexed with N-phenyl-4-((4H-1,2,4-triazol-3-ylsulfanyl)methyl)-1,3-thiazol-2-amine
收藏Protein Data Bank Japan2023-11-08 更新2026-03-21 收录
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Crystal structure of the catalytic domain of MMP-13 complexed with N-phenyl-4-((4H-1,2,4-triazol-3-ylsulfanyl)methyl)-1,3-thiazol-2-amine Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Collagenase 3, ... Authors: Oki, H, Tanaka, Y. Deposit date: 2016-05-13 Release date: 2017-01-18 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.2 Å) Cite: Discovery of Novel, Highly Potent, and Selective Matrix Metalloproteinase (MMP)-13 Inhibitors with a 1,2,4-Triazol-3-yl Moiety as a Zinc Binding Group Using a Structure-Based Design Approach J. Med. Chem., 60, 2017
创建时间:
2016-05-13



