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Transcriptomic analysis of LSD1i-sensitive and resistant AML cells

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE125719
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The goal of this study is to identify the molecular mechanisms underlying the resistance/sensitivity of AML cells to lysine specific demethylase 1 (LSD1) inhibitor. We performed the transcriptomic analysis at the earliest detected and last tested time points in which mTOR was regulated secondary to LSD1i (i.e. 6 and 72h in sensitive KASUMI-1 cells and 24 and 72h in resistant THP-1 cells)
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2020-01-28
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