BindingDB Entry 50018853: Design, Structure-Activity Relationships, and In Vivo Evaluation of Potent and Brain-Penetrant Imidazo[1,2-

Small molecule binding data for protein AP2-associated protein kinase 1, Aurora kinase A, Aurora kinase B, Casein kinase II subunit alpha, Casein kinase II subunit alpha', Cyclin-dependent kinase 2, Cyclin-dependent kinase 5, Cytoplasmic tyrosine-protein kinase BMX, Glycogen synthase kinase-3 alpha, Glycogen synthase kinase-3 beta, Insulin-like growth factor 1 receptor, Interleukin-1 receptor-associated kinase 1, Interleukin-1 receptor-associated kinase 4, MAP kinase-activated protein kinase 2, Mast/stem cell growth factor receptor Kit, Microtubule-associated protein tau, Mitogen-activated protein kinase 14, Non-receptor tyrosine-protein kinase TYK2, Nuclear receptor subfamily 4 group A member 3, Platelet-derived growth factor receptor beta, Protein kinase C theta type, Ribosomal protein S6 kinase alpha-1, Serine/threonine-protein kinase pim-1, Tyrosine-protein kinase BTK, Tyrosine-protein kinase ITK/TSK, Tyrosine-protein kinase JAK1, Tyrosine-protein kinase JAK2, Tyrosine-protein kinase Lck, Tyrosine-protein kinase Lyn, Tyrosine-protein kinase SYK, and Tyrosine-protein kinase TXK, Uniprot O60674, P06239, P07948, P08069, P09619, P10636, P10721, P11309, P19784, P23458, P24941, P29597, P42681, P43405, P49137, P49840, P49841, P51617, P51813, P68400, P97477, Q00535, Q04759, Q06187, Q08881, Q15418, Q16539, Q2M2I8, Q92570, Q96GD4, and Q9NWZ3