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Visible-Light-Promoted C2 Selective Arylation of Quinoline and Pyridine N‑Oxides with Diaryliodonium Tetrafluoroborate

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Figshare2020-01-07 更新2026-04-28 收录
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A protocol of visible-light-promoted C2 selective arylation of quinoline and pyridine N-oxides, with diaryliodonium tetrafluoroborate as an arylation reagent, using eosin Y as a photocatalyst for the construction of N-heterobiaryls was presented. This methodology provided an efficient way for the synthesis of 2-aryl-substituted quinoline and pyridine N-oxides. This strategy has the following advantages: specific regioselectivity, simple operation, good functional group tolerance, and high to moderate yields under mild conditions.

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2020-01-07
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