Role of PC1 on Evs release in mDCT15 cells

NIAID Data Ecosystem2026-03-14 收录

多囊肾病机制研究

基因功能缺失转录组分析

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https://www.ncbi.nlm.nih.gov/sra/SRP388451 数据链接链接失效反馈

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To investigate the role of the loss Pkd1 in mDCT15 cells we compared the transcriptome of wild type and Pkd1-/- mCT15 cells. Overall design: Comparative gene expression profiling analysis of RNA-seq data for mDCT15 wild type and Pkd1-/- cells

创建时间：

2022-11-03

Supplementary Material for: Endocannabinoid System in Polycystic Kidney Disease

多囊肾病机制研究

内源性大麻素系统

Introduction: Autosomal dominant polycystic kidney disease (ADPKD) is a commonly inherited disorder characterized by renal cyst formation. A major pathological feature of ADPKD is the development of i

NIAID Data Ecosystem50

Next Generation Sequencing Facilitates Quantitative Analysis of either Pkd1f/f, Pkd1f/f:HoxB7-Cre mice or Pkd2f/f, Pkd2f/f:HoxB7-Cre mice smallRNA [miRNA-seq]

多囊肾病机制研究

miRNA表达谱分析

Purpose: To reveal the cystogenesis regulatory mechanism by miRNA and miRNA targeted genes in ADPKD mouse models. Method(miRNA-seq): Small RNA sample preparation was done according to Illumina's prot

NIAID Data Ecosystem50

A scalable organoid model of autosomal dominant polycystic kidney disease for disease mechanism and drug discovery

多囊肾病机制研究

类器官药物筛选

Human pluripotent stem cell-derived organoids are models for human development and disease. We report a modified human kidney organoid system that generates thousands of similar kidney organoids, each

NIAID Data Ecosystem20

Next Generation Sequencing Facilitates Quantitative Analysis of either Pkd1f/f, Pkd1f/f:HoxB7-Cre mice or Pkd2f/f, Pkd2f/f:HoxB7-Cre mice transcriptome [RNA-seq]

多囊肾病机制研究

转录组学分析

Purpose: To reveal the cystogenesis regulatory mechanism by miRNA and miRNA targeted genes in ADPKD mouse models. Method (mRNA-seq): In order to construct cDNA libraries with the TruSeq RNA library ki

NIAID Data Ecosystem50

Network Analysis of a Pkd1 -Mouse Model of Autosomal Dominant Polycystic Kidney Disease Identifies HNF4α as a Disease Modifier

多囊肾病机制研究

代谢组学与疾病模型

Autosomal Dominant Polycystic Kidney Disease (ADPKD; MIM ID's 173900, 601313, 613095) leads to end-stage kidney disease, caused by mutations in PKD1 or PKD2. Inactivation of Pkd1 before or after P13 i

NIAID Data Ecosystem40

Role of PC1 on Evs release in mDCT15 cells

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