肺癌数据分析

肺癌是一种起源于肺部支气管黏膜或腺体的恶性肿瘤，是全球范围内最常见的癌症之一，也是癌症死亡的主要原因。本产品提供DNA、RNA的分析流程以及单细胞的分析流程。其中DNA包含点突变、结构变异、融合分析、CNV变异分析。RNAseq除了基因表达差异外，还包括新转录本发现、等位基因特异性表达、转录本和非编码RNA的相互作用。单细胞分析包括细胞类别鉴定、细胞间通讯、单细胞轨迹分析、转录因子的分析。

Lung cancer is a malignant tumor originating from the bronchial mucosa or glands of the lung. It is one of the most common cancers worldwide and the leading cause of cancer-related deaths. This resource provides analytical pipelines for DNA, RNA and single-cell data. For DNA analysis, it covers point mutations, structural variations, fusion analysis, and copy number variation (CNV) analysis. For RNA sequencing (RNA-seq) analysis, in addition to differential gene expression, it also includes de novo transcript discovery, allele-specific expression, and interactions between transcripts and non-coding RNAs. Single-cell analysis encompasses cell type annotation, intercellular communication analysis, single-cell trajectory inference, and transcription factor analysis.

搜集汇总

背景与挑战

背景概述

该数据集专注于肺癌的多组学研究，提供DNA层面的突变/变异分析、RNA层面的表达与转录本分析，以及单细胞层面的细胞类型与功能分析，覆盖肺癌研究的分子到细胞层级关键维度。