Murine ex vivo cultured alveolar macrophages provide a novel tool to study tissue-resident macrophage behavior and function

MexAMs are functionally similar to primary AMs, so we compared their transcriptional profile to different macrophage populations. These included BMDMs, as the macrophage type predominantly used for in vitro studies, arising from myeloid bone marrow progenitor cells, as well as peritoneal macrophages (PMs), a mature TRM population exposed to a different tissue microenvironment. Overall design: mRNA profiles of listed cell types (BALF, PLF, BMDM, mexAM)