FKBP12 in complex with PROTAC 6a2
收藏Protein Data Bank Japan2024-01-24 更新2026-04-19 收录
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FKBP12 in complex with PROTAC 6a2 Descriptor: (2~{S},4~{R})-1-[(2~{S})-2-[2-[2-[2-[4-[(1~{S})-1-[(1~{S},5~{S},6~{R})-10-[3,5-bis(chloranyl)phenyl]sulfonyl-5-ethenyl-2-oxidanylidene-3,10-diazabicyclo[4.3.1]decan-3-yl]ethyl]-1,2,3-triazol-1-yl]ethoxy]ethoxy]ethanoylamino]-3,3-dimethyl-butanoyl]-~{N}-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Peptidyl-prolyl cis-trans isomerase FKBP1A Authors: Meyners, C, Walz, M, Geiger, T.M, Hausch, F. Deposit date: 2023-06-12 Release date: 2023-11-15 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.2 Å) Cite: Discovery of a Potent Proteolysis Targeting Chimera Enables Targeting the Scaffolding Functions of FK506-Binding Protein 51 (FKBP51). Angew.Chem.Int.Ed.Engl., 63, 2024
创建时间：
2023-06-12
