DNA topological stress inhibits DNA replication fork (RF) progression and contributes to DNA replication stress. In Saccharomyces cerevisiae we demonstrate that centromeric DNA and the rDNA array are
Analysis of X chromosome localization within the nucleus via the three-zone assay. Statistical analysis was done using Student’s t-tests. Statistically significant differences (p<0.05) are highlighted
Nucleus, chromatin, and chromosome organization studies heavily rely on fluorescence microscopy imaging to elucidate the distribution and abundance of structural and regulatory components. Three-dimen
Number counts based on DAPI-stained embryos (Figure 4 and File S2) are compared to those expected considering preceding mitotic divisions. Note that expected numbers are overestimates from C9 onward,
