Gene expression in xenograft tumors derived from HCT116 and its oxaliplatin resistant clones. Gene expression in xenograft tumors derived from HCT116 and its oxaliplatin resistant clones

To explore the mechanisms associated with oxaliplatin resistance, we compared gene expression in xenograft tumors derived from human colorectal cancer tumor cells HCT116 and its oxaliplatin resistant clones (HCT/OHP1 and HCT/OHP5). Overall design: Messenger RNA was extracted from xenograft tumors derived from HCT116 and its oxaliplatin resistant clones (HCT/OHP1 and HCT/OHP5). Then gene expression was compared between HCT116 and oxaliplatin resistant clones (HCT/OHP1 and HCT/OHP5).