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Molecular Analysis of the Autocrine TGF-beta Driven Myofibroblastic Differentiation Program in a Novel ex vivo Model

ChEBI2011-04-15 更新2026-07-21 收录

成纤维细胞分化

TGF-β信号通路

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-28634 数据链接链接失效反馈

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Molecular Analysis of the Autocrine TGF-beta Driven Myofibroblastic Differentiation Program in a Novel ex vivo Model

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创建时间：

2011-04-15

乳腺癌分子机制

TGF-β信号通路

In this study, we took advantage of a previously established breast cancer progression cell line model system, which consists of a parental MCF10A (MI) spontaneously immortalized mammary epithelial ce

NIAID Data Ecosystem60

Transforming Growth Factor β Receptor Type 1 Is Essential for Female Reproductive Tract Integrity and Function

雌性生殖道发育

TGF-β信号通路

The transforming growth factor β (TGFβ) superfamily proteins are principle regulators of numerous biological functions. Although recent studies have gained tremendous insights into this growth factor

Figshare2016-01-18 更新50

Latent Transforming Growth Factor Î² Binding Protein 3 Controls Adipogenesis

脂肪形成

TGF-β信号通路

Transforming growth factor-beta (TGFÎ²) is released from cells as part of a trimeric latent complex consisting of TGFÎ², the TGFÎ² propeptides, and either a latent TGFÎ² binding protein (LTBP) orÂ gly

DataONE2022-08-15 更新50

TEM1/endosialin/CD248 promotes pathologic scarring and TGF-β activity through its receptor stability in dermal fibroblasts. TEM1/endosialin/CD248 promotes pathologic scarring and TGF-β activity through its receptor stability in dermal fibroblasts

病理性瘢痕机制

TGF-β信号通路

We established a hypertrophic scar-like animal model using traction force in C57BL/6J mice to demonstrate the crucial mechanistic effect of TEM1 on pathological scarring. Samples from scar areas in sh

NIAID Data Ecosystem50

Immunohistochemical staining for TGF-β1 and TGF-β R1 in grafted veins (n = 6).

移植血管免疫组化

TGF-β信号通路

0, negative staining (−); 1–4, weak staining (+); 5–8, moderate staining (++); and 9–12, intense staining (+++). The Fisher exact test was used for intergroup comparisons of immunohistochemistry score

Figshare2015-12-02 更新50

Molecular Analysis of the Autocrine TGF-beta Driven Myofibroblastic Differentiation Program in a Novel ex vivo Model

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