B-Raf kinase domain in complex with a tetrahydronaphthalene inhibitor
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B-Raf kinase domain in complex with a tetrahydronaphthalene inhibitor Descriptor: (2S)-N-[3-(2-aminopropan-2-yl)-5-(trifluoromethyl)phenyl]-7-[(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-4-yl)oxy]-1,2,3,4-tetrahydronaphthalene-2-carboxamide, Serine/threonine-protein kinase B-raf Authors: Sintchak, M.D, Aertgeerts, K, Yano, J. Deposit date: 2011-01-07 Release date: 2011-03-23 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Design and optimization of potent and orally bioavailable tetrahydronaphthalene raf inhibitors. J.Med.Chem., 54, 2011
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2011-01-07
