Comparison of transcriptome between vector-transduced (control) and TIFAB-transduced murine MLL-AF9 leukemia stem cells Leukemia stem cells (defined as lin−c-kit+Sca1−CD16+CD34+) were sorted by FACS f

NIAID Data Ecosystem20

Effect of depletion or overexpression of CaSR on gene expression in BM-derived Lineage negative AML cells

白血病分子机制

基因表达调控

To investigate the effects of CaSR depletion or overexpression on gene expression in primary AML cells, we compared the gene expression profile of sorted lineage negative cells from the bone marrow of

NIAID Data Ecosystem00

Core transcriptional regulatory circuit controlled by the tal1 complex in human t-cell acute lymphoblastic leukemia (Subseries)

白血病分子机制

转录调控网络

The oncogenic transcription factor TAL1/SCL is aberrantly overexpressed in over 40% of cases of T-cell acute lymphoblastic leukemia (T-ALL), emphasizing the importance of the TAL1-regulated transcript

NIAID Data Ecosystem40

LIN28B is overexpressed in specific subtypes of pediatric leukemia and regulates lncRNA H19 [K562]. Homo sapiens

白血病分子机制

LIN28B基因调控

The stem cell gene LIN28B was recently shown to be overexpressed in a foetal-like subgroup of juvenile myelomonocytic leukaemia. Given the involvement of LIN28B in a variety of solid paediatric cancer

NIAID Data Ecosystem10

Transcriptome analysis of SF3B1-mutation induced changes in K562 cells

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