Discovery of dihydrothieno- and dihydrofuropyrimidines as potent pan Akt inhibitors
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Discovery of dihydrothieno- and dihydrofuropyrimidines as potent pan Akt inhibitors Descriptor: (2R)-3-(1H-indol-3-yl)-1-{4-[(5S)-5-methyl-5,7-dihydrothieno[3,4-d]pyrimidin-4-yl]piperazin-1-yl}-1-oxopropan-2-amine, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha Authors: Dizon, F, Wu, W, Vigers, G.P.A, Brandhuber, B.J. Deposit date: 2010-09-17 Release date: 2010-11-10 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Discovery of dihydrothieno- and dihydrofuropyrimidines as potent pan Akt inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
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2010-09-17
