supplementary materials for manuscript titled “itga4”

Mendeley Data2026-04-09 收录

肿瘤耐药机制

癌症分子靶点

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supplementary materials for manuscript titled “ITGA4 contributes to 5-Fluorouracil resistance by up-regulating PI3K/AKT signaling: evidence from network pharmacology, molecular docking and experimental verification”

Additional file 7 of Novel drug resistance mechanisms and drug targets in BRAF-mutated peritoneal metastasis from colorectal cancer

肿瘤耐药机制

BRCA突变肿瘤

Supplementary Material 7.

DataCite Commons2024-08-17 更新90

YAP activation mediates acquired resistance to ALK inhibitor in ALK rearranged non–small cell lung cancer

肿瘤耐药机制

ALK靶向治疗

To investigate a possible candidate for overcoming the acquired resistance to ALK-TKI, we established an in vitro model of acquired resistance to crizotinib (H3122-CR) by exposing EML4-ALK–positive H3

NIAID Data Ecosystem40

SAKE (Single-cell RNA-Seq Analysis and Klustering Evaluation) Identifies Markers of Resistance to Targeted BRAF Inhibitors in Melanoma Cell Populations. Homo sapiens isolate:451Lu is a selected xenograft aggressive metastatic sub-line of WM164. WM164 is a metastatic human melanoma cell line established from a metastatic site (right upper arm) in a 22-year-old male with stage IV superficial spreading melanoma. 451Lu cell line features the specific V600E (Val600Glu) mutation at codon 600 in the BRAF gene.

单细胞转录组学

肿瘤耐药机制

The goal of this study is to apply the SAKE algorithms to identify drug-resistant cellular populations as human melanoma cells respond to targeted BRAF inhibitors. Single-cell RNA-Seq data from 10x Ge

NIAID Data Ecosystem20

Suppression of adaptive responses to targeted cancer therapy by transcriptional repression [RNA-seq]. Homo sapiens

肿瘤耐药机制

转录组药物响应

Large-scale genomic profiling efforts have facilitated the characterization of molecular alterations in cancers and aided the development of targeted kinase inhibitors for a wide array of cancer types

NIAID Data Ecosystem50

Identification of SLAMF3 (CD229) as an Inhibitor of Hepatocellular Carcinoma Cell Proliferation and Tumour Progression

癌症分子靶点

肿瘤免疫调节

Although hepatocellular carcinoma (HCC) is one of the most common malignancies and constitutes the third leading cause of cancer-related deaths, the underlying molecular mechanisms are not fully under

NIAID Data Ecosystem30

supplementary materials for manuscript titled “itga4”

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