Analysis of polymorphism in 9 merozoite stage expressed <i>P. falciparum</i> genes in a Gambian population sample.

Nt, number of aligned nucleotide positions analysed. •, stop codon in 7 alleles of PF10_0348 (codon removed from analysis). ◊, repeats removed from gene sequences for analysis. aonly one region of msp7 gene (of most dense polymorphism) was studied in the population. b5 complex codons in ama1 not analysed. cless sequence aligned when P. reichenowi added (Pf10_0348 N = 1824, msp7 N = 1041, sera5 N = 600). *p<0.05. **p<0.01. ***p<0.001. Values significantly different to 0 are shown in italics; for ama1 Tajima's D is significant for Domain II (p<0.05) and Domain III (p<0.001), and Fu and Li's F is significant for Domain III (p<0.02); Sequences submitted to Genbank (Accession numbers for population datasets of allele sequences are listed in Supplementary Table S2).