8104baf4-13a1-4a3d-b35c-2863791059ab - samples

NIAID Data Ecosystem2026-03-13 收录

类器官药物筛选

肿瘤靶向治疗

数据链接：

https://www.omicsdi.org/dataset/ega/EGAD00001008445 数据链接链接失效反馈

官方服务：

资源简介：

Functional screening on patient-derived organoids identifies a therapeutic bispecific antibody that triggers EGFR degradation in LGR5+ tumor cellsEGA dataset EGAD00001008445

创建时间：

2022-01-18

SAM Competitive PRMT5 Inhibitor PF-06939999 Demonstrates Antitumor Activity in Splicing Dysregulated NSCLC with Decreased Liability of Drug Resistance

肿瘤靶向治疗

药物耐药机制

Protein arginine methyltransferase 5 (PRMT5) over-expression in hematological and solid tumors methylates arginine residues on cellular proteins involved in important cancer functions including cell c

NIAID Data Ecosystem90

Subsequent treatments after progression on CDK 4/6 inhibitors.

肿瘤靶向治疗

乳腺癌耐药管理

Subsequent treatments after progression on CDK 4/6 inhibitors.

NIAID Data Ecosystem70

FORECAST 1. Feasibility of using Organoid Response to find Effective Treatments for patients with Colorectal cancer After failure of Standard Therapy

类器官药物筛选

转移性结直肠癌治疗

Interventions: This feasibility study involves the collection of fresh tumour tissue from patients with Metastatic Colorectal Cancer ( mCRC) for the purposes of establishing organoid model cultures.Pa

NIAID Data Ecosystem40

肿瘤靶分子临床研究信息数据集

肿瘤靶向治疗

临床研究

聚焦肿瘤靶分子临床研究全流程，整合靶点发现、临床试验设计、疗效数据、安全性评估等核心信息。数据经标准化清洗与专业校验，关联靶点分子结构、作用机制及临床结果，支持科研机构靶点验证、药企药物研发、临床机构方案优化，为靶分子临床转化提供高质量、可溯源的数据支撑。

江苏数据交易所80

Successful BRAF/MEK-inhibition in a young patient with BRAF V600E-mutated extrapancreatic acinar cell carcinoma (HIPO-021)

肿瘤靶向治疗

癌症基因组分析

Pancreatic acinar cell carcinoma (PAC) is a rare but dismal disease with a peak incidence rate around 60 to 70 years of age. Treatment options in case of metastatic disease are limited and often follo

NIAID Data Ecosystem50

8104baf4-13a1-4a3d-b35c-2863791059ab - samples

资源简介：

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