Crystal structure of BACE1 with its inhibitor
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Crystal structure of BACE1 with its inhibitor Descriptor: Beta-secretase 1, CHLORIDE ION, N-[(1R)-1-(4-fluorophenyl)ethyl]-N'-[(2S,3S)-3-hydroxy-1-phenyl-4-(1H-pyrazol-1-yl)butan-2-yl]-5-[methyl(methylsulfonyl)amino]benzene-1,3-dicarboxamide, ... Authors: Chen, T.T, Chen, W.Y, Xu, Y.C. Deposit date: 2011-11-21 Release date: 2012-11-21 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Flexibility of the Flap in the Active Site of BACE1 as Revealed by Crystal Structures and MD simulations to be published
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2011-11-21
