Lipids Maintain Genomic Stability and Full Potency of Murine Embryonic Stem Cells

NIAID Data Ecosystem2026-03-13 收录

干细胞代谢调控

基因组稳定性

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA806916 数据链接链接失效反馈

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Lipids Maintain Genomic Stability and Full Potency of Murine Embryonic Stem Cells

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2022-02-14

Histone H3.3 maintains genome integrity during mammalian development

表观遗传调控

基因组稳定性

Histone H3.3 is a highly conserved histone H3 replacement variant in metazoans, and has been implicated in many important biological processes including cell differentiation and reprogramming. Germlin

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Proteomic profile of MFF overexpression in MCF7 cells

干细胞代谢调控

线粒体蛋白质组学

Elevated mitochondrial biogenesis and metabolism represent key features of breast cancer stem cells (CSCs), whose propagation is conducive to disease onset and progression. Therefore, interfering with

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A single metabolite which modulates lipid metabolism alters hematopoietic stem/progenitor cell behavior and promotes lymphoid reconstitution

干细胞代谢调控

淋巴重建

Fatty acid beta-oxidation (FAO), the breakdown of lipids, is a metabolic pathway used by various stem cells. FAO levels are generally high during quiescence and downregulated with proliferation. The e

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SIRT7 tethering of L1 elements to the nuclear lamina mediates their transcriptional repression

基因组稳定性

表观遗传调控

Long interspersed elements-1 (LINE-1, L1) are retrotransposons that hold the capacity of selfpropagation in the genome with potential mutagenic outcomes. How somatic cells restrict L1 activity and how

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OsMre11 is required for mitosis during rice growth and development

植物分子生物学

基因组稳定性

Meiotic recombination 11 (Mre11) is a relatively conserved nuclease in various species. Mre11 plays important roles in meiosis and DNA damage repair in yeast, humans and Arabidopsis, but little resear

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Lipids Maintain Genomic Stability and Full Potency of Murine Embryonic Stem Cells

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