Phase I/II study of preoperative treatment with capecitabine, oxaliplatin and irinotecan (XELOXIRI) in patients with advanced colorectal cancer
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Interventions: Neo-adjuvant chemotherapy : XELOXIRI 6 cycles Resection : total mesorectal excision or tumor-specific mesorectal excision Adjuvant chemotherapy : XELOX 4 cycles Primary outcome(s): 1) Phase I To determine the recommended dose 2) Phase II pathological complete response rate Study Design: Single arm Non-randomized
创建时间:
2013-02-15



