SGK1 plasmids were commercially purchased from MRC PPU Dundee, UK and have been previously characterised for their function. SGK1 and its variants were subcloned into the pVAX.A120 vector containing,
PDPK1 (PDK1) activates SGK1 by phosphorylating threonine residue T256, located in the activation loop of SGK1. Phosphorylation of SGK1 at S422 facilitates subsequent phosphorylation at T256 (Kobayashi
ENCODES a protein that exhibits 3-phosphoinositide-dependent protein kinase binding; protein serine/threonine kinase activity; tau protein binding; INVOLVED IN cellular response to insulin stimulus; i
