Recruitment of the m6A/Am demethylase FTO to target RNAs by the telomeric zinc finger protein ZBTB48

NIAID Data Ecosystem2026-05-02 收录

RNA表观遗传学

蛋白质-RNA相互作用

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE228608 数据链接链接失效反馈

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This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2024-10-09

Mutations in the RNA Binding Domain of Stem-Loop Binding Protein Define Separable Requirements for RNA Binding and for Histone Pre-mRNA Processing

组蛋白mRNA加工

蛋白质-RNA相互作用

Expression of replication-dependent histone genes at the posttranscriptional level is controlled by stem-loop binding protein (SLBP). One function of SLBP is to bind the stem-loop structure in the 3′

PubMed Central60

m6A IP sequencing analysis of m6A mRNA methylation regulation by FTO in melanoma cells. m6A IP sequencing analysis of m6A mRNA methylation regulation by FTO in melanoma cells

RNA表观遗传学

黑色素瘤分子机制

N6-methyladenosine (m6A) RNA methylation is the most abundant internal chemical modifications in eukaryotic messenger RNA (mRNA) as well as long non-coding RNA (lncRNA). Recently, m6A RNA methylation

NIAID Data Ecosystem50

Exploring the Role of DNMT1 in RNA m⁵C Methylation (Ribo-seq)

RNA表观遗传学

神经退行性机制

DNA methyltransferase 1 (DNMT1) is an enzyme known for DNA methylation maintenance. However, point mutations in its RFTS domain lead to late-onset neurodegeneration such as the autosomal dominant cere

NIAID Data Ecosystem30

PAR-CLIPseq for C-terminal truncated G3BP1 binding RNA

蛋白质-RNA相互作用

PAR-CLIPseq技术

This data aims to screen RNAs that specifically bind to the truncated G3BP1 proteins 259-466aa and 310-466aa, which are different from those binding to the full-length G3BP1. The RNA samples are deriv

NIAID Data Ecosystem50

RNA m6A modification mediated by METTL3 is important for IAP heterochromatin integrity in mESCs (MeRIP-Seq)

RNA表观遗传学

细胞染色质调控

N6-methyladenosine (m6A) methyltransferase METTL3 mainly mediates mRNA m6A methylation and plays important roles in various biological processes. Here we report a chromatin-based role for METTL3 in he

NIAID Data Ecosystem50

Recruitment of the m6A/Am demethylase FTO to target RNAs by the telomeric zinc finger protein ZBTB48

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