Clinical and phenotypic characteristics of the Saguenay�CLac-St-Jean association study sample subjects.

*FEV1 = Geometric mean of the force expiratory volume in one second evaluated for 208 probands and for 683 family members.?PC20 = Concentration of methacholine inducing a 20% fall in FEV1. Geometric mean and SD were obtained from the log transformed PC20 values. Evaluated for 186 probands and for 614 family members.?IgE = Immunoglobulin E serum concentration. Geometric mean and SD were obtained from the log transformed IgE values. Evaluated for 211 probands and 704 family members.��Present asthma or past documented clinical history of asthma. The reported mean age of onset is 7 years among the asthmatic probands and 22 years among the asthmatic family members.��Defined as at least one positive response on skin prick testing (wheal diameter >3 mm at 10 minutes).