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Site-specific methylation of Notch1 controls the amplitude and duration of the Notch1 response

ChEBI2015-03-26 更新2026-07-21 收录

Notch信号通路

蛋白质甲基化功能

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-62528 数据链接链接失效反馈

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Site-specific methylation of Notch1 controls the amplitude and duration of the Notch1 response

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2015-03-26

Notch信号通路

毛发生长

Notch is a key signalling pathway playing multiple and varied functions during development. Notch regulates the selection of cells with a neurogenic fate and maintains a pool of yet uncommitted precur

DataCite Commons2020-09-02 更新810

Mutual Inactivation of Notch Receptors and Ligands Facilitates Developmental Patterning

发育模式形成

Notch信号通路

Developmental patterning requires juxtacrine signaling in order to tightly coordinate the fates of neighboring cells. Recent work has shown that Notch and Delta, the canonical metazoan juxtacrine sign

NIAID Data Ecosystem90

ADAM10 Negatively Regulates Neuronal Differentiation during Spinal Cord Development

脊髓发育调控

Notch信号通路

Members of the ADAM (a disintegrin and metalloprotease) family are involved in embryogenesis and tissue formation via their proteolytic function, cell-cell and cell-matrix interactions. ADAM10 is expr

NIAID Data Ecosystem50

Histone variant H2A.Z deposition and acetylation directs the canonical Notch signaling response

Notch信号通路

组蛋白修饰与转录调控

The study deals with the elucidation of potential interaction partners of the intracellular domain of the transmembrane receptor Notch1, termed NICD. The NICD is released from the cytoplasmic tail of

NIAID Data Ecosystem110

Notch ligand Dll4 impairs the recruitment of hemogenic cells into intra-aortic clusters and limits hematopoietic stem cell production

造血干细胞

Notch信号通路

Hematopoietic stem cells (HSCs) develop from the hemogenic endothelium in the embryonic aorta. In most vertebrates, hemogenic cells protrude into the aortic lumen forming clusters where the hematopoie

干细胞与再生医学数据中心2022-02-20 更新50

Site-specific methylation of Notch1 controls the amplitude and duration of the Notch1 response

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