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High-Depth PacBio Methylome Profiles to Investigate Gene Regulation Mediated by Phase-Variable DNA Methyltransferases in Serogroup B Neisseria meningitidis.

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NIAID Data Ecosystem2026-05-10 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP664409
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资源简介:
Neisseria meningitidis serogroup B is a major cause of meningitis and septicemia. Here, we report high-depth PacBio HiFi genome sequencing and quantitative single-molecule real-time methylomics for strains MC58, B6116/77, and M0579, respectively encoding phase-variable DNA methyltransferases ModA11, ModA12, and ModD1, which are epigenetic regulators pivotal to meningococcal pathogenicity.
创建时间:
2026-02-13
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