Dengue virus non-structural protein 1 suppresses megakaryopoiesis by targeting the FOSB transcription factor

Abstract: This study identifies DENV-NS1 as a critical factor that impairs megakaryocytic differentiation and polyploidization through the downregulation of the transcription factor FOSB. Data Content: This dataset includes: Summary Statistics: The raw numerical values behind all means and standard deviations reported in the article. Figure Datasets (Figures 1–5): The specific numerical values used to generate all primary graphs and figures. Image Analysis Data (Figures 1S–2S): The raw data points extracted from SDS-PAGE images used for quantitative analysis. Flow Cytometry Data (Figure 3S): The percentage values and geometric means (GeoMean) derived from flow cytometry analysis. Note: The raw RNA-seq reads (FASTQ) are hosted separately at NCBI under Accession PRJNA1499955.