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A Catalytic Asymmetric Isatin-Involved Povarov Reaction: Diastereo- and Enantioselective Construction of Spiro[indolin-3,2′-quinoline] Scaffold

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Figshare2016-02-20 更新2026-04-29 收录
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https://figshare.com/articles/dataset/A_Catalytic_Asymmetric_Isatin_Involved_Povarov_Reaction_Diastereo_and_Enantioselective_Construction_of_Spiro_indolin_3_2_quinoline_Scaffold/2455531
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The first catalytic asymmetric isatin-involved Povarov reaction has been established. This method provides an unprecedented approach to access the enantioenriched spiro[indolin-3,2′-quinoline] scaffold with concomitant creation of two quaternary stereogenic centers in high yields and excellent stereoselectivities (all >99:1 dr's, up to 97% ee).
创建时间:
2016-02-20
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