Crystal Structure of human RIPK1 kinase domain in complex with a novel inhibitor
收藏Protein Data Bank Japan2023-11-29 更新2026-03-21 收录
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Crystal Structure of human RIPK1 kinase domain in complex with a novel inhibitor Descriptor: N-[(3S)-7-(2-cyclopropylethynyl)-5-methyl-4-oxidanylidene-2,3-dihydro-1,5-benzoxazepin-3-yl]-5-(phenylmethyl)-4H-1,2,4-triazole-3-carboxamide, Receptor-interacting serine/threonine-protein kinase 1 Authors: Su, H.X, Xie, H, Nie, T.Q, Li, M.J, Xu, Y.C. Deposit date: 2021-07-15 Release date: 2022-01-19 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.21 Å) Cite: Potent and Selective RIPK1 Inhibitors Targeting Dual-Pockets for the Treatment of Systemic Inflammatory Response Syndrome and Sepsis. Angew.Chem.Int.Ed.Engl., 61, 2022
创建时间：
2021-07-15
