RNA-seq data for non-targeting siRNA and lncRNA LOL siRNA transfection in MCF-7 cells
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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http://data.iscr.ac.cn/Article?id=c5700331435afcd42b6b22419c9c3837
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资源简介:
To elucidate which portions of signaling pathways LOL influences in luminal breast cancer, RNA-seq analysis was performed in siLOL MCF-7 cell lines. Eight hundred eighty-three downregulated genes and 1182 upregulated genes (fold change â¥1.5) were detected after LOL knockdown. Gene set enrichment analysis (GSEA) of hallmarks indicated that the gene sets related to DNA_Repair, G2M_Checkpoint, E2F_Targets and MYC_Targets were positively correlated with LOL downregulation.
提供机构:
Fudan University Shanghai Cancer Center
创建时间:
2022-02-20



