Crystal structure of Staphylococcus aureus ClpP in complex with ZG180

Crystal structure of Staphylococcus aureus ClpP in complex with ZG180 Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, (6S,9aS)-6-[(2S)-butan-2-yl]-8-(naphthalen-1-ylmethyl)-4,7-bis(oxidanylidene)-N-[4,4,4-tris(fluoranyl)butyl]-3,6,9,9a-tetrahydro-2H-pyrazino[1,2-a]pyrimidine-1-carboxamide, ATP-dependent Clp protease proteolytic subunit, ... Authors: Wei, B.Y, Gan, J.H, Yang, C.-G. Deposit date: 2022-01-03 Release date: 2022-11-16 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Anti-infective therapy using species-specific activators of Staphylococcus aureus ClpP. Nat Commun, 13, 2022