Crystal structure of the bromodomain of ATAD2 with triazolopyridazine (cpd 22)
收藏Protein Data Bank Japan2024-05-01 更新2026-04-19 收录
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Crystal structure of the bromodomain of ATAD2 with triazolopyridazine (cpd 22) Descriptor: (1R,9S)-13-[[3-methyl-8-[(1-methylpiperidin-4-yl)amino]-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]carbonyl]-11,13-diazatricyclo[7.3.1.0^{2,7}]trideca-2,4,6-trien-10-one, ATPase family AAA domain-containing protein 2, SULFATE ION Authors: Patel, S.J, Winter-Holt, J.J. Deposit date: 2021-11-09 Release date: 2022-01-19 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.96 Å) Cite: Discovery of a Potent and Selective ATAD2 Bromodomain Inhibitor with Antiproliferative Activity in Breast Cancer Models. J.Med.Chem., 65, 2022
创建时间：
2021-11-09
