Age-related alterations in meningeal immunity drive impaired CNS lymphatic drainage

NIAID Data Ecosystem2026-05-01 收录

神经免疫学

衰老相关脑功能退化

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE217314 数据链接链接失效反馈

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This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2023-04-28

RNA sequencing microglia depletion model

神经免疫学

RNA测序分析

We developed an experimental model system in mice, in which microglia can be depleted selectively and temporarily from the prefrontal cortex (PFC) during a defined window of adolescence (6 weeks of ag

NIAID Data Ecosystem120

Table_2_Peripheral Humoral Immune Response Is Associated With the Non-motor Symptoms of Parkinson’s Disease.DOCX

神经免疫学

帕金森病运动症状

BackgroundNon-motor symptoms are common in Parkinson’s disease (PD) and can even be used as part of the supportive criteria for diagnosis. Chronic inflammation is involved in every stage of PD. Disord

NIAID Data Ecosystem60

Additional file 10: of Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer’s disease

神经免疫学

单细胞转录组学

3D viSNE representation of microglial modules: DAM (Red) and Homeostatic (Black) genes identified by single-cell RNAseq mapped to WGCNA modules. (HTML 3818 kb)

Figshare2018-05-22 更新50

Next Generation Sequencing Facilitates Single Cell Analysis of Wild Type and Monocyte-Depleted Brain Transcriptomes

单细胞转录组学

神经免疫学

Methods: Cells isolated from the whole brains of naive wild type, infected wild type, and infected CCR2-DTR mice were sort-purified on live CD45hi cells from five biological replicates and pooled. Sor

NIAID Data Ecosystem70

Comparison of the therapeutic efficacy of 50 and 10mg/kg NSSL-MPS in the acute EAE mice model.

神经免疫学

药物疗效评估

a- Significant difference from the control group P<0.0001 b- Significant difference from NSSL-50mg/kg group P<0.005 c- Significant difference from the control group P<0.05. Comparison of the therapeut

NIAID Data Ecosystem60

Age-related alterations in meningeal immunity drive impaired CNS lymphatic drainage

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