TESS/TFSEARCH predicted binding motifs across the β-globin locus.

1Microarray data shown as fold change in expression from day 21 to day 56;2Nucleotide abbreviations: N = G, A or T; K = G or T, Y = T or C, M = A or C, R = A or G;3The Log-likelihood scores is a statistical measure representing the probability that a TF binding site exists in the region analyzed; we used a cutoff ≥7.0. The higher the score the more likely the predicted sequence binds the target TF indicated.4Number of binding sites identified in the different regions in the β-locus. For example there are 15, 21 and 10 predicted GATA1 binding sites in the LCR, γ-globin and β-globin regions respectively.TESS/TFSEARCH predicted binding motifs across the β-globin locus.