Enhancing Autophagy in CD11c+ Antigen Presenting Cells as a Therapeutic Strategy for Acute Respiratory Distress Syndrome and Lung Inflammation
收藏NIAID Data Ecosystem2026-05-01 收录
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To investigate the role of autophagy in CD11c+ APCs in a mouse model of Poly(I:C)-induced ALI/ARDS We generated two animal models; mice with a deletion of autophagy-related gene 5 (Atg5) specifically in CD11c+ APCs to impair autophagy and mice with overexpression of transcription factor EB (Tfeb), a regulator of autophagy, in CD11c+ APCs to constitutively induce autophagy.
创建时间：
2023-09-27
