The list consists of the human orthologues of worm genes that, when targeted by RNAi, suppress the paralysis phenotype in Aβ-expressing worms (n = 78 genes).
Nuclear receptors (NRs) are master regulators of insect ecdysis, metamorphosis, and reproduction, ideal targets for eco-friendly pest control. However, no comprehensive functional screening of the ent
A genome-scale RNAi screen was performed in a mammalian cell-based assay to identify modifiers of mutant huntingtin toxicity. Ontology analysis of suppressor data identified processes previously impli
