TMC-95 based biphenyl-ether macrocycles: specific proteasome inhibitors

TMC-95 based biphenyl-ether macrocycles: specific proteasome inhibitors Descriptor: BENZYL [12-(2-AMINO-2-OXOETHYL)-4-NITRO-10,13-DIOXO-15-[(PROPYLAMINO)CARBONYL]-2-OXA-11,14-DIAZATRICYCLO[15 .2.2.1~3,7~]DOCOSA-1(19),3(22),4,6,17,20-HEXAEN-9-YL]CARBAMATE, Proteasome component C1, Proteasome component C11, ... Authors: Groll, M, Goetz, M, Kaiser, M, Weyher, E, Moroder, M. Deposit date: 2006-04-18 Release date: 2006-07-11 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.81 Å) Cite: TMC-95-Based Inhibitor Design Provides Evidence for the Catalytic Versatility of the Proteasome. Chem.Biol., 13, 2006