Type III interferon signaling
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The recently identified type III interferon group consists of three IFN-λ (lambda) genes encoding molecules called IFN-λ1, IFN-λ2 and IFN-λ3 (also called IL29, IL28A and IL28B respectively). These IFNs signal through a receptor complex consisting of IL10R2 (also called CRF2-4) and IFNLR1 (also called CRF2-12).
近期鉴定出的III型干扰素家族包含三个编码IFN-λ(lambda)分子的基因,分别命名为IFN-λ1、IFN-λ2和IFN-λ3(分别也被称为IL29、IL28A和IL28B)。这些干扰素通过由IL10R2(亦称CRF2-4)和IFNLR1(亦称CRF2-12)组成的受体复合物进行信号传导。
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