Impact of circadian rhythm in obtaining reference profiles of exRNAs in healthy individuals (2). Impact of circadian rhythm in obtaining reference profiles of exRNAs in healthy individuals (2)

Blood was collected from healthy individuals in the morning, afternoon and evening, and plasma analyzed by RNA-seq. Plasma from two donors were not included due to excessive hemolysis in samples from two data points. One datapoint -afternoon- from donor 3 was also not included due to excessive hemolysis. Overall design: 17 samples from 6 subjects, 3 time points (8:30am, 2:30pm, 6:30pm) from each subject.