Study cases according to mutation status in pre- and post-chemotherapy samples and their clinicopathological and tumor response characteristics (n = 40 pairs).

Abbreviations: C1, + = tumor response ≥25% after cycle 1 chemotherapy, C1,— = tumour response 50mm in greatest dimension; T4, tumor of any size with direct extension to the chest wall and/or to the skin (ulceration or skin nodules); WT, wildtype; -, negative/no; +, positive/yesa Status of respective mutation in pre-chemotherapy sampleb Status of respective mutation in post-chemotherapy samplec Arm A, randomized to receive doxorubicin in first cycle; Arm B, randomized to receive docetaxel in first cycled Age in yearsStudy cases according to mutation status in pre- and post-chemotherapy samples and their clinicopathological and tumor response characteristics (n = 40 pairs).