Crystal Structure of human KRAS G12C covalently bound to nopinone-derived naphthol compound 21
收藏Protein Data Bank Japan2025-03-05 更新2026-04-19 收录
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Crystal Structure of human KRAS G12C covalently bound to nopinone-derived naphthol compound 21 Descriptor: 1,2-ETHANEDIOL, 1-{6-[(4P,6R,8R)-3-fluoro-4-(3-hydroxynaphthalen-1-yl)-7,7-dimethyl-5,6,7,8-tetrahydro-6,8-methanoquinolin-2-yl]-2,6-diazaspiro[3.4]octan-2-yl}propan-1-one, GUANOSINE-5'-DIPHOSPHATE, ... Authors: Mohr, C. Deposit date: 2024-11-08 Release date: 2025-02-26 Last modified: 2025-03-05 Method: X-RAY DIFFRACTION (1.18 Å) Cite: Identification of Structurally Novel KRAS G12C Inhibitors through Covalent DNA-Encoded Library Screening. J.Med.Chem., 68, 2025
创建时间：
2024-11-08
