Highly Diastereoselective Synthesis of Tetrahydropyridines by a C–H Activation–Cyclization–Reduction Cascade
收藏Figshare2016-02-22 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Highly_Diastereoselective_Synthesis_of_Tetrahydropyridines_by_a_C_H_Activation_Cyclization_Reduction_Cascade/2543548
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资源简介：
A versatile reaction cascade leading to highly substituted 1,2,3,6-tetrahydropyridines has been developed. It comprises rhodium(I)-catalyzed C–H activation–alkyne coupling followed by electrocyclization and subsequent acid/borohydride-promoted reduction. This one-pot procedure affords the target compounds in up to 95% yield with >95% diastereomeric purity.
创建时间：
2016-02-22
