Enantioselective Construction of Spirocyclic Oxindole Derivatives with Multiple Stereocenters via an Organocatalytic Michael/Aldol/Hemiacetalization Cascade Reaction
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https://figshare.com/articles/dataset/Enantioselective_Construction_of_Spirocyclic_Oxindole_Derivatives_with_Multiple_Stereocenters_via_an_Organocatalytic_Michael_Aldol_Hemiacetalization_Cascade_Reaction/3219109
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资源简介:
An efficient organocatalytic Michael/aldol/hemiacetalization
cascade
reaction for construction of enantioenriched spirocyclic oxindoles
fused with tetrahydropyrane has been developed. The desired highly
functionalized 5′,6′-dihydro-2′H,4′H-spiro[indoline-3,3′-pyran]-2-one
derivatives containing multiple stereogenic centers were obtained
in moderate to high chemical yields and with high stereoselectivities.
创建时间:
2016-05-16



