TargetGene

TargetGene database provides a comprehensive map of SNP-to-gene connections across a wide range of human tissues and cell types, dissecting the associations between genetic risk factors and complex human traits at multiple molecular levels.

TargetGene is a comprehensive database that provides a comprehensive connection atlas linking genetic variants to target genes, covering diverse human tissues and cell types. This database integrates multi-omic sequencing data at both single-cell and bulk levels, identifies specific target genes across 45 tissues and 539 cell types via a multi-omic combinatorial strategy, and collects thousands of GWAS results from large-scale cohorts of diverse ethnic groups.

搜集汇总

背景与挑战

背景概述

TargetGene是一个综合数据库，通过整合单细胞与批量多组学数据，建立了遗传变异与靶基因的连接图谱。它覆盖45种组织和539种细胞类型中的特异性靶基因，并收集了数千个跨族裔人群的GWAS结果。