m6A is decoded by modified tRNAs to coordinate mRNA decay.
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2025-05-10
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The RNA N6-methyladenosine regulates chromatin remodeling and transcription [seq_mettl3ChIP]. The RNA N6-methyladenosine regulates chromatin remodeling and transcription [seq_mettl3ChIP]
The N6-methyladenosine (m6A) has been shown to regulate stability and translation of messenger RNA (mRNA) in various biological processes. Here, we show that the knockout of the m6A writer Mettl3 or a
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N6-Methyladenosine (m6A) and N6,2'-O-dimethyladenosine (m6Am) are abundant mRNA modifications that regulate transcript processing and translation. The role of both, here termed m6A/m, in the stress re
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m6A RNA modification controls cell fate transition in mammalian embryonic stem cells
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Additional file 2: of Widespread changes in mRNA stability contribute to quiescence-specific gene expression patterns in a fibroblast model of quiescence
Gene ontology tables of genes with fast or slow decaying genes in both proliferating and quiescent fibroblasts. (XLSX 69Â kb)
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A Mutation in cnot8, Component of the Ccr4-Not Complex Regulating Transcript Stability, Affects Expression Levels of Developmental Regulators and Reveals a Role of Fgf3 in Development of Caudal Hypothalamic Dopaminergic Neurons
While regulation of the activity of developmental control genes at the transcriptional level as well as by specific miRNA-based degradation are intensively studied, little is known whether general cel
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