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RUNX3 promotes the development of MDS via suppressing expression level of Runx1 and enhancing activation of Myc pathway in the absence of Tet2.. Mus musculus

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJDB8198
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Analysis of Hematopoietic stem and progenitor cells (HSPCs) expressing Runx3. The RUNX transcription factors have a critical role in normal and malignant hematopoiesis including myeloproliferative neoplasms (MPN) and myelodysplastic syndromes (MDS). Results provide insight into the role of Runx3 in the development of MDS.
创建时间:
2019-04-17
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