liver miRNA expression profiles of HCC/CCC patients

Cholangiocellular carcinoma (CCC) is one of the liver originated malignant tumors. There are big difference between hepatocellular carcinoma (HCC) and CCC in respect of treatment and prognosis. Because the advanced CCC that are not indicated surgically resection was quite poor prognosis, it is important to detect within an early stage. However, there is no useful biomarker for diagnosis of CCC at present. In order to establish useful biomarker for CCC, we attempt to analyze the miRNA expression profile in exosome.