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ATF4-Histone 2-Hydroxyisobutyrylation Feedback Loop Drives Sepsis-Induced Inflammation

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NIAID Data Ecosystem2026-05-10 收录
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The roles and mechanism of lysine histone 2-hydroxyisobutyrylation (khib) in the acute inflammation phase of sepsis remain unknown. We aimed to investigate the roles and underlying mechanisms of histone H4K5-khib (H4K5-hib) in sepsis-induced inflammation models in vivo and in vitro.

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2025-12-08
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