Risk Reclassification Table Comparing 90-Day Mortality Risk Strata According to MELD and 5vMELD ^*.

*Deaths and survivors at 90 days of follow-up, ignoring censored observations. †Observed mortality at 90-days estimated from Kaplan-Meier curve using all observations within each cell. In total, 3921 patients (26%) were reclassified according to 5vMELD (in cells with ≥20 observations); 3591 (92%) were correctly reclassified. The reclassification calibration statistic for MELD is 273.2 (P<0.0001) vs. 60.0 for 5vMELD (P<0.0001). Reclassification improvement with 5vMELD is 7.2% (174−94 of 1113) among deaths and 7.2% (1736 – 955 of 10802) among survivors, leading to a net reclassification improvement of 14.4% (95% CI 11.4 to 17.5%; P<0.0001).