Memory performance as assessed in the Object Recognition Test (ORT).

Bold data indicate intact memory performance, i.e., when animals were able to distinguish the old from the new object. At the 2-hour interval, a significant condition×sex interaction was observed (P = 0.013). At the 3-hour interval, a significant overall effect of 5-Htt genotype was observed (P = 0.038). See results section for more details. Data in the first three columns represent mean relative discrimination index (RDI) ± S.E.M. The last column shows the average exploration times (the average time spent exploring each object during T1 and T2, averaged over the 3 intervals), which did not differ between groups. Abbreviations: WT, wild-type; M, males; F, females; C, control offspring; PS, prenatally stressed offspring. N = 7–10 mice/group.